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VipD is required for endosomal avoidance by L. pneumophila. (A and B) CHO-FcγRII cells producing GFP-tagged Rab5a(Q79L) were challenged with the indicated L. pneumophila strains. Colocalization of LCVs with GFP-Rab5a(Q79L) 10 min after uptake was determined by immunofluorescence microscopy. (Scale bar, 1 μm.) *P < 0.05; **P < 0.01; ***P < 0.005 (Student t test).
