Table 2. Univariate and Multivariate factors associated with FLAIR ratio hyperintensity.
| Univariate analysis of FLAIR ratio | Multivariate analysis of FLAIR ratio Adjusted |
|||||
|---|---|---|---|---|---|---|
| β coefficient* | 95% CI | P value | β coefficient* | 95% CI | P value | |
|
|
|
|||||
| Age | 0.001 | (−0.002 to 0.003) | 0.69 | -- | -- | |
| Sex (female) | −0.011 | (−0.045 to 0.023) | 0.52 | -- | -- | |
| IV tPA treatment (Y) | 0.004 | (−0.029 to 0.037 | 0.82 | -- | -- | |
| Time from last seen well to MRI (hrs) | 0.009 | (0.001 to 0.016) | 0.027 | 0.010 | (0.003 to 0.017) | 0.01 |
| DWI volume | −0.002 | (−0.077 to 0.073) | 0.95 | -- | -- | |
| MMP-2 | −0.078 | (−0.270 to 0.114) | 0.42 | -- | -- | |
| MMP-9 | 0.155 | (0.078 to 0.232) | <0.001 | 0.162 | (0.086 to 0.238) | <0.001 |
*
The β coefficient is the magnitude change in FLAIR ratio per unit or category. IV tPA denotes intravenous tissue plasminogen activator. DWI, diffusion weighted image. MMP, matrix metalloproteinase.