TABLE II. In vivo suppression of Plasmodium berghei in infected mice and average mouse survival after oral and subcutaneous treatment with 500 mg/kg/day of extracts of Tachia grandiflora in the Peters 4-day suppressive test.
| Parasite inhibition (%) | ||||||
|---|---|---|---|---|---|---|
| Oral | Subcutaneous | Average survivaltime ± SD | ||||
| Sample | Day 5 | Day 7 | Day 5 | Day 7 | Oral | Subcutaneous |
| Root water extract | 59 | 24 | 45 | 0 | 24 ± 3 | 22 ± 2 |
| Root methanol extract | 39 | 11 | 27 | 0 | 21 ± 2 | 20 ± 3 |
| Leaf ethanol extract | 24 | 0 | 6 | 0 | 19 ± 3 | 22 ± 1 |
| Chloroquine, 10 mg/kg/day | 99 | 98 | 99 | 100 | > 40 | > 40 |
| Control, blank | 0 | 0 | 0 | 0 | 20 ± 5 | 22 ± 3 |
SD: standard deviation.