TABLE. Pattern of intrathecal synthesis of human T-lymphotropic virus type 1 (HTLV-1) antibodies (core en envelope proteins) in 20 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients.
GD21 | p19/gp21 | p24 | p26 | p28 | p32 | p36 | gp46 | p53 | rgp46-I | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Patient | S | C | S | C | S | C | S | C | S | C | S | C | S | C | S | C | S | C | S | C |
H01 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | 0 | ++ | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H02 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ |
H03 | + | ++ | + | + | + | ++ | + | + | + | + | 0 | 0 | + | + | 0 | 0 | 0 | 0 | + | ++ |
H04 | 0 | ++ | + | + | + | ++ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | + | ++ |
H05 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H06 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | 0 | ++ | + | ++ | 0 | 0 | 0 | ++ | + | ++ |
H07 | 0 | ++ | + | ++ | + | ++ | 0 | ++ | 0 | ++ | 0 | ++ | 0 | 0 | 0 | ++ | 0 | 0 | + | ++ |
H08 | + | ++ | + | ++ | + | ++ | 0 | ++ | 0 | ++ | 0 | 0 | 0 | ++ | 0 | 0 | 0 | 0 | + | ++ |
H09 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H10 | + | ++ | + | + | + | ++ | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
H11 | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | ++ |
H12 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H13 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H14 | + | ++ | + | ++ | + | ++ | + | + | + | ++ | + | + | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H15 | + | ++ | + | + | + | ++ | + | + | + | + | + | + | + | + | 0 | 0 | + | + | + | ++ |
H16 | + | ++ | + | + | + | ++ | + | + | + | + | + | + | + | ++ | + | ++ | + | ++ | + | ++ |
H17 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ |
H18 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ |
H19 | + | ++ | + | + | + | ++ | + | + | + | + | + | + | + | ++ | 0 | ++ | 0 | ++ | + | ++ |
H20 | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ | + | ++ |
Patients with intrathecal synthesis of HTLV-1 Ab (n) | 19 | 13 | 19 | 12 | 13 | 11 | 15 | 12 | 13 | 19 |
Ab: antibody; C: cerebrospinal fluid; reference for intrathecal synthesis of HTLV-1 antibodies: presence of bands only in CSF or higher intensity in CSF than in serum; S: serum; 0: no band; +: weak band; ++: intense band.