Table 1.
Changes in RV with 14‐, 21‐, and 28‐HySu compared to Normoxia
| Group | Normoxia | 14‐HySu | 21‐HySu | 28‐HySu |
|---|---|---|---|---|
| RVSP | 26 ± 1 | 37 ± 2* | 41 ± 2* | 45 ± 1* |
| RVEDP | 0.8 ± 0.1 | 1.2 ± 0.1 | 1.4 ± 0.1* | 1.4 ± 0.2* |
| LV+S | 78.3 ± 2.2 | 77.8 ± 4.3 | 79.5 ± 2.6 | 78.9 ± 4.5 |
| BW | 25.3 ± 0.6 | 23.2 ± 0.4 | 23.2 ± 0.9 | 24.1 ± 0.6 |
| Fulton index | 0.26 ± 0.01 | 0.40 ± 0.02* | 0.43 ± 0.01* | 0.44 ± 0.03* |
| Hct | 46 ± 1.1 | 75 ± 2.2* | 74 ± 1.2* | 61 ± 0.4* |
| RV compliance | 0.53 ± 0.03 | 0.36 ± 0.04* | 0.36 ± 0.03* | 0.30 ± 0.01* |
| τ | 5.7 ± 0.5 | 3.1 ± 0.6* | 4.9 ± 0.4 | 5.0 ± 0.3 |
| EDV | 23.8 ± 1.0 | 26.4 ± 3.1 | 28.9 ± 2.2 | 29.9 ± 1.5 |
| ESV | 9.8 ± 0.6 | 12.4 ± 2.6 | 14.8 ± 1.9 | 16.5 ± 1.3 |
| SV | 14.7 ± 1.0 | 14.9 ± 1.4 | 14.2 ± 1.0 | 13.4 ± 0.7 |
| HR | 552 ± 16 | 597 ± 17 | 591 ± 19 | 597 ± 17 |
| Aortic pressure | 53 ± 5 | 55 ± 3 | 59 ± 1 | 55 ± 1 |
N = 8–9 per group. RVSP (mmHg), RV end‐diastolic pressure (RVEDP, mmHg), LV + Septum mass (LV+S, mg), body weight (BW, g), Fulton index (mg/mg), hematocrit (Hct,%), RV compliance (μL/mmHg), relaxation factor τ (msec), end‐diastolic volume (EDV, μL), end‐systolic volume (ESV, μL), stroke volume (SV, μL), heart rate (HR, beats/min), aortic pressure (mmHg).
*
P < 0.05 versus Normoxia.