Table 1.
CT and Hemodynamic analysis of resting systolic and diastolic function 20 weeks post aortic banding.
| CON | HF | HF‐CsA | |
|---|---|---|---|
| Systolic function | |||
| HR (beats/min) | 126 ± 5 | 106 ± 4* | 114 ± 4§ |
| MAP (mmHg) | 53 ± 11 | 59 ± 4 | 86 ± 8*,† |
| LV ESV (mL) | 32 ± 3 | 24 ± 2 | 43 ± 3† |
| LV ESP (mmHg) | 65 ± 7 | 81 ± 6 | 109 ± 9* |
| LV EF (%) | 54 ± 2 | 56 ± 4 | 47 ± 3 |
| LA ESV (mL) | 25 ± 2 | 28 ± 1 | 44 ± 3*,† |
| LA EF (%) | 47 ± 1 | 40 ± 5 | 33 ± 2* |
| Diastolic function | |||
| LV EDV (mL) | 70 ± 8 | 57 ± 6 | 80 ± 4† |
| LV EDP (mmHg) | 11 ± 1 | 11 ± 1 | 15 ± 1*,† |
| LA EDV (mL) | 47 ± 2 | 46 ± 1 | 65 ± 3*,† |
| Morphology | |||
| LV Mass (g) | 85 ± 4 | 87 ± 3 | 103 ± 3*,† |
| LV Mass:Vol (g/mL) | 1.2 ± 0.1 | 1.7 ± 0.1*,‡ | 1.3 ± 0.1 |
Values are means ± SE. HR, heart rate; MAP, mean arterial pressure; LV ESV, left ventricular end systolic volume; LV ESP, left ventricular end systolic pressure; LV EF, left ventricular ejection fraction; LA ESV, left atrial end systolic volume; LA EF, left atrial ejection fraction; LV EDV,, left ventricular end diastolic volume; LV EDP,, left ventricular end diastolic pressure; LA EDV, left atrial end diastolic volume; LV mass:Vol, LV free wall mass:LV EDV ratio. Significance is indicated at *P < 0.05 versus CON; †P < 0.05 versus HF; ‡P < 0.05 versus HF‐CsA; §P = 0.08 versus CON.