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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Metabolism. 2013 Jan 26;62(6):873–887. doi: 10.1016/j.metabol.2013.01.001

Fig. 2.

Fig. 2

Homozygous leptin receptor-deficient obese Zucker rats and homozygous leptin-deficient obese ob/ob mice had significantly higher body weights and the levels of the hepatic expression of p27 were significantly lower compared with heterozygous lean controls. (A) Body weights of the obese Zucker rats (n=3) and the lean control Zucker rats (n=3). (B) Levels of the hepatic expression of p27 in the obese Zucker rats (n=3) and the lean control Zucker rats (n=3). (C) Body weights of the obese ob/ob mice (n=3) and the lean control mice (n=3). (D) Levels of the hepatic expression of p27 in the obese ob/ob mice (n=3) and the lean control mice (n=3). (E) A hypothetical diagram showing how the lower levels of the expression of p27 could increase the risk of developing cancer.