TABLE 4.
Posterior Stromal Dystrophies.
Posterior Stromal Dystrophies | IVCM Findings | Reference / Number of Patients | Type of IVCM |
---|---|---|---|
Cornea Farinata | – Highly reflective small particles in the cytoplasm of keratocytes in the deep stroma adjacent to the corneal endothelial layer30 | (30) Kobayashi, Ohkubo et al./ 2 | (30) Scanning Slit |
Pre-Descemet’s dystrophy (PDCD) | – Intra- and extra-cellular hyperreflective inclusions pleomorphic in shape, 30 to 80 μm in size immediately anterior to Descemet’s mem- brane and prominent sub-basal nerves29 | (29) Lanza et al./1 (32) Ye et al./ 1 |
(29) Scanning Slit (32) Scanning Slit |
– Intracellular particles inside enlarged kera- tocytes with abnormally visible intercellular processes.32 | |||
– No involvement of the anterior and mid-stroma29 | |||
Fleck’s dystrophy (FCD) | – Intracellular reflective spherical matter 1–18 μm enclosed in cyst-like structures and large 50–110 μm doughnut-like particles in the mid- and posterior stroma5,33,34 | (5) Travesi et al./ 2 (33) Pan et al./ 9 (34) Grupscheva et al./ 1 |
(5) Laser Scanning (33) Scanning Slit (34) Scanning Slit (36) Scanning Slit |
– Basal nerves with hyperreflective inclusions and reduced sub-basal nerves36 | (36) Frueh et al./ 3 | ||
Central cloudy dystrophy of Francois (CCDF) | – Multiple dark striae in the posterior stroma adja- cent to the endothelium appearing as vertical, horizontal, oblique, or reticular lines37 | (37) Kobayashi, Sugiyama et al./ 2 | (37) Scanning Slit |
Posterior amorphous corneal dystrophy (PACD) | – Microfolds and diffuse hyperreflective sheet-like extracellular opacities with spikes in the deep posterior stroma.38 | (38) Erdem et al./ 1 | (38) Scanning Slit |