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. Author manuscript; available in PMC: 2014 Mar 31.
Published in final edited form as: Semin Ophthalmol. 2012 Sep-Nov;27(0):107–116. doi: 10.3109/08820538.2012.707276

TABLE 4.

Posterior Stromal Dystrophies.

Posterior Stromal Dystrophies IVCM Findings Reference / Number of Patients Type of IVCM
Cornea Farinata – Highly reflective small particles in the cytoplasm of keratocytes in the deep stroma adjacent to the corneal endothelial layer30 (30) Kobayashi, Ohkubo et al./ 2 (30) Scanning Slit
Pre-Descemet’s dystrophy (PDCD) – Intra- and extra-cellular hyperreflective inclusions pleomorphic in shape, 30 to 80 μm in size immediately anterior to Descemet’s mem- brane and prominent sub-basal nerves29 (29) Lanza et al./1
(32) Ye et al./ 1
(29) Scanning Slit
(32) Scanning Slit
– Intracellular particles inside enlarged kera- tocytes with abnormally visible intercellular processes.32
– No involvement of the anterior and mid-stroma29
Fleck’s dystrophy (FCD) – Intracellular reflective spherical matter 1–18 μm enclosed in cyst-like structures and large 50–110 μm doughnut-like particles in the mid- and posterior stroma5,33,34 (5) Travesi et al./ 2
(33) Pan et al./ 9
(34) Grupscheva et al./ 1
(5) Laser Scanning
(33) Scanning Slit
(34) Scanning Slit
(36) Scanning Slit
– Basal nerves with hyperreflective inclusions and reduced sub-basal nerves36 (36) Frueh et al./ 3
Central cloudy dystrophy of Francois (CCDF) – Multiple dark striae in the posterior stroma adja- cent to the endothelium appearing as vertical, horizontal, oblique, or reticular lines37 (37) Kobayashi, Sugiyama et al./ 2 (37) Scanning Slit
Posterior amorphous corneal dystrophy (PACD) – Microfolds and diffuse hyperreflective sheet-like extracellular opacities with spikes in the deep posterior stroma.38 (38) Erdem et al./ 1 (38) Scanning Slit