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. Author manuscript; available in PMC: 2014 Mar 31.
Published in final edited form as: Semin Ophthalmol. 2012 Sep-Nov;27(0):107–116. doi: 10.3109/08820538.2012.707276

TABLE 5.

Endothelial Dystrophies.

Endothelial Dystrophies IVCM Findings Reference / Number of Patients Type of IVCM
Fuchs’ endothelial corneal dystrophy (FECD) – Large round hyporeflective images with occasional central highlight at endothelium31, 39,41 (31) Yeh et al./ 1
(39) Chiou, Kaufman et al./ 1
(31) Scanning Slit
– Hyperreflective pleomorphic and polymegathic endothelial cells which cannot be identified individually43 (41) Dong et al./ 19 (39) Tandem Scanning
– Stroma with blurred collagen fibers and increased background illumination43 (43) Hecker et al./ 10
(44) Rokita-Wala et al./ 21
(41) Scanning Slit
– Sparse population of keratocytes in the anterior stroma43 (45) Mustonen et al./ 11 (43) Tandem Scanning
– Lacunae and 5–20 μm wide dark bands against increased back- ground reflection in posterior stroma44,45 (44) Scanning Slit
– Thickened Descemet’s 44,45
– Absent subbasal nerve plexus45 (45) Scanning Slit
Posterior – Endothelial surface with craters, streaks, and cracks31,47 (31) Yeh et al. (31) Scanning Slit
Polymorphous Corneal Dystrophy (PPCD) – Vesicular lesions, rounded dark areas with doughnut-like appearance47- Railroad track lesions - band-like dark areas enclosing smaller lighter cells resembling epithelium47 (47) Patel, Grupcheva et al./ 6 (48) Chiou, Kaufman, et al./ 2 (47) Scanning Slit
– Descements with patchy hyperreflective areas and hyporeflective round images and bands48 (48) Tandem Scanning