TABLE 5.
Endothelial Dystrophies | IVCM Findings | Reference / Number of Patients | Type of IVCM |
---|---|---|---|
Fuchs’ endothelial corneal dystrophy (FECD) | – Large round hyporeflective images with occasional central highlight at endothelium31, 39,41 | (31) Yeh et al./ 1 (39) Chiou, Kaufman et al./ 1 |
(31) Scanning Slit |
– Hyperreflective pleomorphic and polymegathic endothelial cells which cannot be identified individually43 | (41) Dong et al./ 19 | (39) Tandem Scanning | |
– Stroma with blurred collagen fibers and increased background illumination43 | (43) Hecker et al./ 10 (44) Rokita-Wala et al./ 21 |
(41) Scanning Slit | |
– Sparse population of keratocytes in the anterior stroma43 | (45) Mustonen et al./ 11 | (43) Tandem Scanning | |
– Lacunae and 5–20 μm wide dark bands against increased back- ground reflection in posterior stroma44,45 | (44) Scanning Slit | ||
– Thickened Descemet’s 44,45 | |||
– Absent subbasal nerve plexus45 | (45) Scanning Slit | ||
Posterior | – Endothelial surface with craters, streaks, and cracks31,47 | (31) Yeh et al. | (31) Scanning Slit |
Polymorphous Corneal Dystrophy (PPCD) | – Vesicular lesions, rounded dark areas with doughnut-like appearance47- Railroad track lesions - band-like dark areas enclosing smaller lighter cells resembling epithelium47 | (47) Patel, Grupcheva et al./ 6 (48) Chiou, Kaufman, et al./ 2 | (47) Scanning Slit |
– Descements with patchy hyperreflective areas and hyporeflective round images and bands48 | (48) Tandem Scanning |