Mean (±S.E.M) total ambulation time (sec) of juvenile and young adult rats treated at either PND 2–5 (A&C) or PND 11–14 (B&D) with 0.5mg/kg/day or 10mg/kg/day doses of Terbutaline. Animals numbers for these studies are as follows: A&C; Saline (n=42), 0.5mg/kg/day APP™ and Sigma (n=55,55), 10mg/kg/day APP™ and Sigma (n=50,48), B&D; Saline (n=34),0.5mg/kg/day APP™andSigma (n=45,50), 10mg/kg/day APP™ and Sigma (n=48,47). Statistical differences are indicated by the following: * p<0.05 vs saline group, † p<001 10mg/kg/day Sigma vs 10mg/kg/day APP™, ‡ p< 0.05 0.5mg/kg/day APP™ vs 10mg/kg/day APP™.