Mean (±S.E.M) total resting time (sec) of juvenile and young adult rats treated at either PN2–5 (A&C) or PND 11–14 (B&D) with 0.5mg/kg/dayand 10mg/kg/day doses of APP™ or Sigma terbutaline. There were no significant differences among the groups in animals injected between PND 11–14. Animal numbers for these studies were as follows: A&C; Saline (n=42), 0.5mg/kg/dayAPP™ and Sigma (n=55,55), 10mg/kg/dayAPP™ and Sigma (n=50,48), B&D; Saline (n=34), 0.5mg/kg/dayAPP™ and Sigma (n=45,50), 10mg/kg/dayAPP™ and Sigma (n=48,47). Statistical differences are indicated by the following: * = p<.05vs saline group, and ‡ = p<0.05 10mg/kg/day Sigma vs 10mg/kg/dayAPP™.