Figure 4. Sigma terbutaline decreases time spent on rotarod.
Latency to fall (sec) at 30-RPM for adult rats treated at PND 2–5 (A) or at PND11–14 (B) with 10mg/kg/day of terbutaline from Sigma. Adult rats injected with terbutaline from Sigma at either PND2–5 or PND11–14 had impaired motor coordination signified by significantly less time spent on the rotarod. Animal numbers for these studies were as follows: Animal numbers for these studies were as follows: PND2–5; Saline (n=42), 0.5mg/kg/day APP™ and Sigma (n=55,55), 10mg/kg/day APP™ and Sigma (n=50,48), PND11–14; Saline (n=34), 0.5mg/kg/day APP™ and Sigma (n=45,50), 10mg/kg/day APP™ and Sigma (n=48,47). Statistical differences are reported as *0.5mg/kg/day of terbutaline from Sigma was p< 0.05 compared to animals in the saline, 0.5mg/kg/day terbutaline from APP™, and 10mg/kg/day from Sigma terbutaline groups.