Table 2.
Microgels | Maximum release (M) |
Half-time (T, days) |
Slope at half time |
|
---|---|---|---|---|
Loading: 200 µg ml−1 DOX | ||||
HG-0 | 0.70 ± 0.01 | 0.71 ± 0.05 | 0.27 ± 0.02 | |
HG-SMA50 | 0.341 ± 0.002 | 1.78 ± 0.02 | 0.068 ± 0.009 | |
HG-SMA100 | 0.223 ± 0.009 | 2.4 ± 0.2 | 0.039 ± 0.005 | |
HG-SMA200 | 0.18 ± 0.02 | 4.1 ± 0.7 | 0.019 ± 0.003 | |
Loading: 400 µg ml−1 DOX | ||||
HG-0 | 1.09 ± 0.02 | 0.93 ± 0.05 | 0.35 ± 0.02 | |
HG-SMA50 | 0.36 ± 0.01 | 1.7 ± 0.1 | 0.070 ± 0.006 | |
HG-SMA100 | 0.14 ± 0.01 | 2.3 ± 0.4 | 0.024 ± 0.006 | |
HG-SMA200 | 0.104 ± 0.008 | 4.6 ± 1.7 | 0.009 ± 0.001 | |
pH | Medium | |||
3 | dH2O | 0.98 ± 0.04 | 0.9 ± 0.1 | 0.4 ± 0.1 |
5 | dH2O | 0.27 ± 0.03 | 1.9 ± 0.5 | 0.40 ± 0.01 |
5 | PBS | 0.70 ± 0.02 | 1.4 ± 0.1 | 0.14 ± 0.01 |
7.4 | PBS | 0.50 ± 0.05 | 2.3 ± 0.4 | 0.07 ± 0.01 |