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. 2014 Mar 31;9(3):e93494. doi: 10.1371/journal.pone.0093494

Figure 2. GO and GSEA analysis on hypoxia, HIF1 and HIF2 target genes.

Figure 2

A. GSEA terms that are enriched in HIF1, HIF2 and hypoxia transcriptomes. B. Examples of enriched GSEA terms for the HIF1 transcriptomes are shown. C. GSEA with hypoxia transcriptome and a >2fold TGFβ upregulated dataset in CB CD34+ cells. D. CB CD34+ cells were transduced with the indicated overexpression vectors at normoxia and/or cultured under hypoxic conditions for 24 hours. Q-RT-PCR was performed for SLC2A1 and SLC2A3. (e.v. =  empty vector).