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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Vet Comp Oncol. 2013 May 15;13(3):246–254. doi: 10.1111/vco.12038

Figure 4.

Figure 4

GS-424044 and GS-343074 induce apoptosis in canine tumour cells. A representative cell line, Abrams, was treated with increasing concentrations of GS-424044 and GS-343074 for 48 h. (A) The percentage of apoptotic cells was detected by flow cytometry using annexin V/PI double staining. (B) Apoptosis was assessed by counting the percentage of annexin V-positive cells. Early apoptosis, annexin-V(+), PI(−); late apoptosis, annexin-V(+), PI(+); total apoptosis, early apoptosis + late apoptosis. Similar were seen in all cell lines used in this study.