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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Vet Comp Oncol. 2013 May 15;13(3):246–254. doi: 10.1111/vco.12038

Table 2.

Calculated IC50 and IC25 values in seven canine neoplastic cell lines following 5 d of treatment with GS-343074 or GS-424044

IC50/IC25 (nmol/L)
Drug C-TAC CML-1 CML-6M CMT-12 CMT-27 DEN-HSA Abrams D17
343074 19.0/10.4 51.4/7.3 55.3/5.1 4.6/2.0 3.7/1.7 180.0/56.4 6.4/2.8 10.0/5.3
424044 NA/NA 78.6/22.8 61.6/24.0 78.8/42.6 35.6/21.5 NA/NA 104.1/73.3 10.7/4.4

NA, not achieved.

GS analogue was administered to cells in MEM supplemented with 10% (C/10) FBS.