TABLE 2.
SNP Association Analysis
| SNP | gene | Chromosome | MAF Caucasian | Location | p value (unadjusted) | p value (adjusted)+ |
|---|---|---|---|---|---|---|
| rs11788318 | TLR4 | 9 | NA | INTERGENIC | 0.008 | 0.655 |
| rs4837494 | TLR4 | 9 | 0.158 | INTERGENIC | 0.031 | 0.98 |
| rs10116253 | TLR4 | 9 | 0.25 | INTERGENIC | 0.007 | 0.625 |
| rs1927914 | TLR4 | 9 | NA | INTERGENIC | 0.023 | 0.94 |
| rs1554973 | TLR4 | 9 | 0.2 | INTERGENIC | 0.021 | 0.93 |
| rs4963049 | MUC5AC/B | 11 | 0.133 | INTERGENIC | 0.033 | 0.99 |
| rs8097137 | SMAD2 | 18 | 0.217 | INTERGENIC | 0.032 | 0.985 |
| rs17663887 | SMAD4 | 18 | NA | INTRON | 0.011 | 0.756 |
MAF- minor allele frequency from HapMap-CEU (CEPH:Utah Residents with Northern and Western European Ancestry)
+
adjusted p-values corrected for multiple testing with permutation testing