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(A) GPIb/IX specificity as detected by MAIPA in two independent assays (OD: optical density). No anti-β3 (i.e. anti-GPIIIa) antibodies were detected (black bars, below the dotted black line). Only anti-GPIb antibodies were detected (light gray bars, above dotted black line). Control was normal human sera. (B) Ristocetin-induced (i.e. GPIb-VWF-mediated) platelet aggregation was inhibited by patient sera (5× dilution). Control was normal human sera.
