Table 3.
Blood loss, hematologic data, and allogeneic blood transfusion
| Preoperative Hb subgrouping | Control group (n = 234) | Tranexamic acid group (n = 154) | Significance | ||
|---|---|---|---|---|---|
| Hb ≥ 12 g/dL (n = 199) | Hb < 12 g/dL (n = 35) | Hb ≥ 12 g/dL (n = 132) | Hb < 12 g/dL (n = 22) | ||
| Intraoperative blood loss (mL) | 409 ± 198 | 388 ± 163 | 0.274 | ||
| 414 ± 199 | 380 ± 191 | 394 ± 165 | 355 ± 150 | 0.402 | |
| Preoperative Hb (g/dL) | 13.5 ± 1.6 | 13.3 ± 1.4 | 0.229 | ||
| Preoperative hematocrit (%) | 40.5 ± 4.8 | 40.0 ± 4.1 | 0.229 | ||
| Early Hb reduction (g/dL) | 0.24 ± 0.12 | 0.23 ± 0.12 | 0.541 | ||
| Early hematocrit reduction (%) | 1.1 ± 0.4 | 1.1 ± 0.4 | 0.454 | ||
| Final Hb reduction (g/dL) | 2.20 ± 1.36 | 1.87 ± 1.10 | 0.010† | ||
| 2.34 ± 1.37 | 1.37 ± 0.93 | 2.00 ± 1.10 | 1.07 ± 0.68 | 0.000‡ | |
| Final hematocrit reduction (%) | 6.6 ± 4.1 | 5.6 ± 3.3 | 0.010† | ||
| 7.02 ± 4.10 | 4.11 ± 2.80 | 6.01 ± 3.30 | 3.22 ± 2.04 | 0.000‡ | |
| Estimated blood loss (mL) | 819 ± 695 | 695 ± 499 | 0.041† | ||
| 865 ± 726 | 561 ± 402 | 736 ± 507 | 448 ± 371 | 0.002‡ | |
| Packed RBC transfusion | 82 (35%) | 26 (17%) | 0.000* | ||
| 61 (31%) | 21 (60%) | 20 (15%) | 6 (27%) | 0.000* | |
Values are mean ± SD; * chi-square test; †Student’s t-test; ‡analysis of variance (post hoc Bonferroni test); Hb = hemoglobin; Hct = hematocrit; RBC = red blood cells.