Immunohistochemical expression of p63, p40 (DB), and p40 (CB) in IDC and metaplastic carcinoma. In IDCs, cancer cells showed more frequent nuclear positivity, with p40 (CB) exhibiting the greatest positivity, then p63 and p40 (DB) (top panels). Squamous subtypes of metaplastic carcinomas showed positive activity for all the myoepithelial markers in the cancer cells (middle panels). Matrix-producing types showed positive activity exclusively for p40 (CB) (bottom panels).