Table 2.
Clinical and laboratory features of twenty-one reported in situ MCL cases
| Case | Age/Sex | Site of Bx | Other sites | BM | PB | Management | F/U (yr) | Status | CD5 | Comosite lymphoma | Other pathology |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 29/F | Inguinal LN | LNs | Yes | Yes | W&W | 19.5 | AWD | - | - | - |
| 2 | 72/F | Submandibular LN | No | Yes | Yes | W&W | 12 | AWD | - | - | Granuloma |
| 3 | 42/F | Cervical LN | No | No | No | W&W | 1 | AND | - | - | Breast Ca |
| 4 | 84/F | Spleen | No | N/A | No | W&W | 1.4 | Died | - | FL | Colon Ca |
| 5 | 42/M | Supclaviculal LN | No | No | N/A | RT | 1.7 | AND | - | - | Castleman disease |
| 6 | 59/M | Cervical LN | No | No | No | W&W | 5 | AND | - | - | Thyroid ca |
| 7 | 65/F | LN | No | Yes | N/A | Chemo | 0.5 | AND | - | - | Granuloma |
| 8 | 40/M | Cervical LN | No | N/A | N/A | N/A | N/A | N/A | - | FL | - |
| 9 | 70/M | Cervical LN | No | N/A | No | W&W | 4 | MCL | - | - | - |
| 10 | 70/F | Nasopharynx | No | No | No | W&W | 3 | AND | + | - | - |
| 11 | 58/M | Intestine | No | Yes | No | Chemo | 1.4 | AND | + | - | - |
| 12 | 42/F | LNs, GIT | LNs | Yes | No | Chemo | 6 | AND | + | - | - |
| 13 | 78/F | Lacrimal gland | No | No | No | N/A | N/A | N/A | + | eMZL | - |
| 14 | 72/F | Cervical | No | N/A | No | RT | 2 | AND | + | NMZL | Breast Ca |
| 15 | 82/M | Oropharynx | LT | N/A | Yes | W&W | 3 | AWD | + | CLL/SLL | - |
| 16 | 82/M | LN | No | No | No | Chemo | 1.5 | AND | + | CLL/SLL | - |
| 17 | 80/M | Inguinal LN | LNs | Yes | Yes | Chemo | N/A | N/A | + | CLL/SLL | - |
| 18 | 80/M | Cervical LN | No | No | No | Chemo | 1.5 | Died | + | FL | - |
| 19 | 65/F | Intramammal LN | LNs | No | No | Chemo | 5 | AND | + | FL | - |
| 20 | 65/M | Appendix | No | N/A | N/A | W&W | 4 | MCL | + | - | - |
| 21 | 68/M | Mediastinal LN | No | N/A | N/A | W&W | 1 | AND | N/A | - | - |
AND, alive with no disease; AWD, alive with disease; Bx, biopsy; BM, bone marrow; Ca, carcinoma; Chemo, chemotherapy; CLL/SLL, chronic lymphocytic leukemia/small lymphocytic lymphoma; eMZL, extranodal marginal zone lymphoma; F, female; FL, follicular lymphoma; F/U, follow up; GIT, gastrointestinal; LN, lymph node; LT, lymphoid tissue; M, male; N/A, not applicable; NMZL, nodal marginal zone lymphoma; PB, peripheral blood; RT, radiation therapy; W&W, watch and wait; yr, year.