Table 1.
Malignant mesonephric mixed tumors in the literature and the present case
| Cases | Age | Symptom | Site | Size | Sarcomatous component | Mesonephric remnants/hyperplasia | Figo stage | Treatment | Follow-up |
|---|---|---|---|---|---|---|---|---|---|
| 1 [6] | 65 | PMB | Cervix | 3 cm | Spindle cells, osteosarcoma | Yes | Ib | RAH+BSO+RT | 23 mo, NED |
| 2 [4] | 37 | Postcoital bleeding | Cervix | NA | Spindle cells | Yes | Ib | Hyst+BSO+LD+ChT | 11 yr, AWD |
| 3 [4] | 40 | Menorrhagia+ cervical polyp | Cervix | NA | Spindle cells | Yes | Ib | Hyst+BSO+RT | 2.3 yr, NED |
| 4 [4] | 73 | Vaginal bleeding | Cervix | NA | Spindle cells | Yes | Ib | Hyst+BSO+RT | 3 yr, NED |
| 5 [4,7] | 39 | Menorrhagia | Cervix | NA | Spindle cells, osteosarcoma | Yes | Ib | Hyst+BSO | 6.2 yr, DOD |
| 6 [8] | 37 | Intermenstrual bleeding, Endometrial polyp | Uterus (posterior wall) | 3.5 cm | Spindle cells | No | Ic | Hyst+BSO | 45 mo, NED |
| 7 [8] | 38 | Coitalgia | Vagina | NA | Spindle cells | NA | NA | tumorectomy | NA |
| 8 [8] | 54 | Vaginal bleeding | Cervix | 6 cm | Spindle cells | Yes | IIa | Hyst+BSO+LD+ omentectomy | 7 mo, DOD |
| 9 [8] | 54 | NA | Cervix | 3.5 cm | Spindle cells, chondrosarcoma | Yes | Ib | Hyst+BSO+LD+ omentectomy | 13 mo, NED |
| 10 [8] | 62 | NA | Cervix | 8 cm | Spindle cells, rhabdomyosarcoma | No | IVb | Hyst+BSO+ChT+RT | 36 mo, AWD |
| 11 [5] | NA | NA | NA | NA | Spindle cells | NA | NA | NA | NA |
| 12 [11] | 63 | PMB | Cervix | 1.8 cm | Spindle cells | Yes | IIa | RAH+BSO+LD | 10 mo, NED |
| 13 (Our case) | 59 | Tumor rupture | Cervix | 6.3 cm | Spindle cells | Yes | IIIb | Hyst+BSO+LD+ ChT+RT | 4 mo, NED |
AWD: alive with disease; BSO: bilateral salpingo-oophorectomy; ChT: chemotherapy; DOD: died of disease; Hyst: hysterectomy; LD: lymphadenectomy; mo: months; NA: not available; NED: no evidence of disease; PMB: postmenopausal bleeding; RAH: radical hysterectomy; RT: radiotherapy; yr: year.