Table 3.
Number of validated true/false sSNVs detected using the five tools in the lung cancer samples
| Tool |
Lung tumors (n = 18) |
|
Lung cancer cell lines (n = 7) |
|
Total
a
|
|
|
||
|---|---|---|---|---|---|---|---|---|---|
|
TP |
FP |
TP |
FP |
TP |
FP | ||||
| # High quality | # Low quality | # High quality | # Low quality | # High quality | # Low quality | ||||
| JointSNVMix |
30 |
17 |
6 |
49 |
0 |
11 |
79 |
17 |
17 |
| MuTect |
30 |
19 |
11 |
47 |
0 |
7 |
77 |
19 |
18 |
| SomaticSniper |
33 |
17 |
10 |
47 |
0 |
9 |
80 |
17 |
19 |
| Strelka |
27 |
17 |
8 |
51 |
0 |
10 |
78 |
17 |
18 |
| Varscan 2 | 35 | 8 | 5 | 51 | 0 | 13 | 86 | 8 | 18 |
aTotal is the sum of #sSNVs found in lung tumors and lung cancer cell lines.
FP: false-positive sSNVs; TP: true-positive sSNVs.