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Somatic mutation of STAG2 in metastatic PDA. (A) Flow cytometry analysis and sorting of a 3.2 N aneuploid population in primary pancreas tissue from rapid autopsy specimen UNMC 11R. (B) Whole genome aCGH plot of the 3.2 N population. (C) Detection of somatic mutation in forward (3.2 N-F) and reverse (3.2 N-R) sequences in the 3.2 N genome. Mutation was not detected in the matching 2.0 N population sorted from the same tissue.
