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Cell cycle specific heat responses of human cells. γ-H2AX refers to the phosphorylation of the histone variant H2AX at serine-139. DSBs, DNA double-stranded breaks; SSBs, DNA single-stranded breaks; sensitivity refers to the frequency of cell death in the different cell cycle stages.
| G1 | S | G2 | |
|---|---|---|---|
| γ-H2AX | low | high | low |
| DSBs | yes | no | yes |
| SSBs | no | yes | no |
| sensitivity | low | high | low |
