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. Author manuscript; available in PMC: 2014 Apr 9.
Published in final edited form as: Stem Cells Dev. 2013 Mar 5;22(12):1851–1860. doi: 10.1089/scd.2012.0658

Figure 7. Plural pluripotent stem cell compartments.

Figure 7

The cell subsets identified based on the expression of the cell surface pluripotency markers TRA-1-60, TRA-1-81, SEEA3, SEEA4 and CD24 in the in HSSC and LSSC subpopulations of M4C7 (hiPSCs) (A) and HUES1 (B) and HD291 (ES) (C) cells are detailed as bar plots. Results were plotted as tree diagrams using the KALUSA software. Each subset is represented by a different color. This analysis shows that there is no superimposition of the compartments defined by the expression of cell surface markers and SSC intensity. Data are the mean ± SEM of three independent experiments. (D) Schematic representation of the stem cell compartments defined by cell surface pluripotency markers and SSC, the permanent exchange between these compartments and the preferential exit toward apoptosis for HSSC cells and toward differentiation for LSSC cells.