Table 3. Multivariate Predictors Of Early Postoperative All-Cause In-Hospital Mortality Following Vascular Surgery In Patients ≥ 40 Years Of Age.

	p-value and odds ratio (95% CI)
	Derivation model (n = 631)		Entire cohort (n = 829)
Pre-operative mortality model
Age (per 1-year increase)	0.056	1.03 (1.0–1.06)	0.067	1.02 (1.0–1.05)
Creatinine > 180 μmol.l-1	< 0.001	6.43 (3.48–11.86)	< 0.001	5.36 (3.01– 9.55)
Chronic beta-blocker therapy	0.002	2.48 (1.38–4.48)	0.01	2.02 (1.18–3.46)
No chronic statin therapy	0.023	2.81 (1.15–6.83)	0.02	2.51 (1.12–5.64)
Postoperative mortality model
Age (per 1-year increase)	0.001	1.05 (1.02–1.09)	0.001	1.05 (1.02–1.08)
Creatinine > 180 μmol.l-1	< 0.001	5.08 (2.50–10.31)	< 0.001	4.35 (2.24–8.42)
Surgery out of hours × no chronic statin therapy	< 0.001	8.27 (3.36–20.38)	< 0.001	5.31 (2.29–12.30)
Last mean daily HR (per beat per minute increase)	0.08	1.02 (1.0–1.04)	< 0.001	1.03 (1.02–1.05)
Last mean daily HR × ‘last mean daily SBP < 100 or > 179 mmHg’	< 0.001	1.02 (1.01–1.03)	< 0.001	1.02 (1.01–1.03)
Last mean daily HR × withdrawal of chronic beta-blockade	< 0.001	1.02 (1.01–1.03)	< 0.001	1.01 (1.01–1.02)

CI: confidence interval; HR: heart rate; SBP: systolic blood pressure.