Table 4.
Multivariable adjusted relative risk (RR) and 95% CIs for ischemic stroke by fetuin-A quartiles.
| Quartiles of Fetuin-A | |||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 |
P for linear trend |
|
| Range (g/L) | <0.38 | 0.38–<0.45 | 0.45–<0.53 | 0.53–1.2 | |
| Cases/Controls | 108/114 | 136/115 | 102/115 | 111/113 | |
| Model 1 | 1.00 | 1.24 (0.86–1.78) | 0.93 (0.63–1.37) | 1.03 (0.69–1.54) | 0.75 |
| Model 2 | 1.00 | 1.18 (0.81–1.72) | 0.86 (0.57–1.28) | 0.98 (0.65–1.49) | 0.59 |
| Model 3 | 1.00 | 1.30 (0.87–1.93) | 0.98 (0.64–1.51) | 1.03 (0.66–1.60) | 0.72 |
Model 1: Conditional on matching factors (age, race/ethnicity, menopausal status, hormone use, smoking)
Model 2: Model 1 + aspirin use, alcohol intake, physical activity, alternate healthy eating index 2010, current post-menopausal hormone use
Model 3: Model 2 + history of diabetes, elevated cholesterol, high blood pressure, and CHD or revascularization, HbA1c, ln(total cholesterol/HDL-C), ln(triglycerides) and ln(hs-CRP)