Table 5.
Multivariable adjusted relative risk (95% CI) of ischemic stroke subtypes by fetuin A quartiles
| Quartiles of Fetuin-A | |||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 |
P for linear trend |
|
| Range (g/L) | <0.38 | 0.38–<0.45 | 0.45–<0.53 | 0.53–1.2 | |
| Thrombotic Stroke | |||||
| Cases/Controls | 75/74 | 92/70 | 65/84 | 74/78 | |
| Model 1 | 1.00 | 1.30 (0.82–2.06) | 0.74 (0.46–1.19) | 0.92 (0.56–1.51) | 0.31 |
| Model 2 | 1.00 | 1.26 (0.78–2.04) | 0.69 (0.42–1.14) | 0.90 (0.53–1.52) | 0.27 |
| Model 3 | 1.00 | 1.44 (0.85–2.42) | 0.89 (0.52–1.53) | 1.05 (0.60–1.84) | 0.65 |
| Embolic Stroke | |||||
| Cases/Controls | 31/31 | 33/41 | 32/26 | 34/32 | |
| Model 1 | 1.00 | 0.84 (0.43–1.63) | 1.24 (0.60–2.59) | 1.08 (0.53–2.22) | 0.59 |
| Model 2 | 1.00 | 0.70 (0.32–1.53) | 1.12 (0.48–2.65) | 1.03 (0.46–2.29) | 0.63 |
| Model 3 | 1.00 | 0.76 (0.33–1.73) | 1.26 (0.49–3.22) | 1.11 (0.48–2.58) | 0.55 |
Model 1: Conditional on matching factors (age, race/ethnicity, menopausal status, hormone use, smoking)
Model 2: Model 1 + aspirin use, alcohol intake, physical activity, alternate healthy eating index 2010
Model 3: Model 2+history of diabetes, elevated cholesterol, high blood pressure, and CHD or revascularization, HbA1c, ln(Total cholesterol/ HDL-C), ln (triglycerides) and ln(hs-CRP)