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. 2014 Apr;143(4):513–524. doi: 10.1085/jgp.201311118

Table 1.

Summary of cell-SPOC parameters used for the discussion on the experimental findings of OM

Parameter Physiological meaning +OM
Parameter change Amplitude Frequency
α Crossbridge attachment rate
η Molecular frictional constant for crossbridge formation

Our mathematical model (Sato et al., 2011) predicts that OM decreases frequency via an increase in α and an increase in η, but the compound hardly changes amplitude because the effect of an increase in α is offset by that of an increase in η (see Results and discussion). Amplitude, cell-SPOC amplitude; frequency, cell-SPOC frequency. Arrows, directions of change.