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Reduction or elimination of αB-crystallin in SOD1 transgenic mice does not alter aggregation in spinal cord tissue. Spinal cords were extracted in non-ionic detergent and electrophoresed in 18% Tris-Glycine gels. Immunoblots were probed with hSOD1 antiserum. A. Detergent-insoluble (20 μg). B. Detergent-soluble (5 μg). The image shown is representative of 3 repetitions of the experiment.
