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Toxicity.
| Adverse event | Grade
|
Total | ||||
|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | ||
| Leukopenia | 23 | 2 | 0 | 0 | 0 | 25 |
| Thrombocytopenia | 24 | 1 | 0 | 0 | 0 | 25 |
| Anemia | 12 | 10 | 3 | 0 | 0 | 25 |
| Other hematologic | 24 | 1 | 0 | 0 | 0 | 25 |
| Hearing | 21 | 0 | 4 | 0 | 0 | 25 |
| Constitutional | 12 | 9 | 1 | 2 | 1 | 25 |
| Dermatologic | 15 | 6 | 4 | 0 | 0 | 25 |
| Gastrointestinal | 5 | 11 | 5 | 4 | 0 | 25 |
| Hemorrhage | 23 | 2 | 0 | 0 | 0 | 25 |
| Infection | 24 | 0 | 1 | 0 | 0 | 25 |
| Lymphatics | 24 | 1 | 0 | 0 | 0 | 25 |
| Musculoskeletal | 22 | 1 | 1 | 1 | 0 | 25 |
| Metabolic | 13 | 8 | 2 | 2 | 0 | 25 |
| Neuropathy | 21 | 2 | 1 | 1 | 0 | 25 |
| Ocular | 24 | 1 | 0 | 0 | 0 | 25 |
| Pain | 17 | 7 | 0 | 1 | 0 | 25 |
| Pulmonary | 23 | 2 | 0 | 0 | 0 | 25 |
