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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Gynecol Oncol. 2011 Oct 28;124(3):569–574. doi: 10.1016/j.ygyno.2011.10.022

Table 4.

Association of biomarkers with survival.

Biomarker Progression free survival
Overall survival
HR Adjusted HRa HR
pERK (intensity)b 1.36 0.99 0.94
pERK (H-value) 1.45 0.74 0.88
pERK (percentage) 1.45 0.74 0.88
Ki-67 (H-value) 0.28c 2.00 0.72
Ki-67 (percentage) 0.63 0.56 0.39

HR = unadjusted hazard ratio for the relevant endpoint with the biomarker evaluated at higher levels to lower levels.

a

Adjusted hazard ratio modeled with platinum sensitivity and performance status factors.

b

pERK was dichotomized into cases with 0+ intensity (8 patients) versus cases with 1+ or 2+ intensities (11 patients).

c

Data suggest an association by permutation test.