Skip to main content
. 2013 Dec 6;77(3):563–570. doi: 10.1021/np400817j

Table 3. Cytotoxicity and Inhibition of the Cytopathic Effect (CPE) by Compounds Isolated from G. glabra as Determined in MDCK Cells.

  50% CPE inhibitory concentration [μM]a
 
code J/8178/09 HK/68 50% cytotoxic concentration [μM]b
1 29.7%c 48.1%c 135 ± 36.3
2 36.1%c n.a.d 336 ± 38.4
3 38.2 ± 4.79 42.6 ± 0.49 123 ± 48.3
4 n.a.d n.a.d 25.4 ± 2.58
5 34.7 ± 14.8 24.2%c 90.8 ± 34.9
6 48.4%c 31.2%c 39.2 ± 15.9
7 34.2%c n.a.d 79.7 ± 29.9
8 n.a.d n.a.d >144
9 n.a.d n.a.d >144
10 n.a.d n.a.d 301 ± 25.5
11 n.a.d n.a.d >239
12 49.6%c n.a.d 126 ± 34.5
oseltamivir 0.03 ± 0.01 0.004 ± 0.002 n.d.e
a

n = 2 to 3, each concentration once.

b

n = 3, each concentration in triplicate.

c

Percentage of maximal inhibition of the CPE at a concentration of 50 μM.

d

Not active (up to 50 μM).

e

Not determined.