Figure 3.

Spatial memory retention in mice during the Morris water maze probe trial following the first day of hidden platform training. (a) Juvenile-RCI mice showed an impairment of hippocampal-dependent spatial memory during the day 3 and day 4 probe trials. (b) All of the adult mice, showed memory retention in the water maze by spending most of their time in target quadrant which contained hidden platform. For all four treatments, when time spent in the target quadrant was compared to all other quadrants there was a significant (p < 0.05) preference. Each bar represents the mean of 8–10 mice; error bars are standard error of the mean (SEM).