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. 2013 Oct 29;90(3):214–223. doi: 10.3109/09553002.2014.859761

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© 2014 Informa UK, Ltd.

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Figure 5. — Total number of activated microglia (CD68⁺) and newly born microglia (BrdU⁺/CD68⁺) per mm² in the dentate subgranular zone of the Juvenile-RCI cohort. (a) In the contralateral hemisphere, there was a no significant group difference in the total numbers of activated microglia (p = 0.606). There was a significant group difference for newly born microglia (p = 0.027). There were minor but insignificant increases in total numbers of activated microglia after radiation only and RCI. (b) In the ipsilateral hemisphere, there was a significant group difference for CD68⁺ cells (p = 0.01) and BrdU⁺/CD68⁺ (p = 0.009). RCI significantly increased in the number of activated microglia compared to sham-treated animals. Percentage change compared with sham-treated animals. Each bar represents the mean of 8–10 mice; error bars are standard error of the mean (SEM).