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. 2013 Oct 29;90(3):214–223. doi: 10.3109/09553002.2014.859761

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© 2014 Informa UK, Ltd.

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Figure 6. — Total number of BrdU⁺ cells and BrdU⁺/NeuN⁺ cells in the dentate subgranular zone of the Adult-RCI cohort. (a) In the contralateral hemisphere, there was a significant group difference for BrdU⁺ cells (p = 0.029) and BrdU⁺/NeuN⁺ (p = 0.015). Radiation significantly decreased the numbers BrdU⁺ cells and BrdU⁺/NeuN⁺ neurons in radiation only and RCI mice (p < 0.05). Percentage change compared with sham-treated animals. (b) In the ipsilateral hemisphere, there was a significant group difference for BrdU⁺ cells (p = 0.027). RCI significantly increased the numbers of BrdU⁺ cells compared to radiation and trauma only (p < 0.05). In terms of newly born neurons, there was a trend toward a group difference (p = 0.0508). Percentage change compared with sham-treated animals. Each bar represents the mean of 9–10 mice; error bars are standard error of the mean (SEM).