Table 3.
Adverse events in patients with HER2+ breast cancer treated with lapatinib plus capecitabine (n = 26)
| Adverse event | Any grade, n (%) | Grade 3–4, n (%) |
|---|---|---|
| Hand-foot syndrome | 9 (34.5) | 1 (3.8) |
| Diarrhea | 12 (46) | 2 (7.6) |
| Fatigue | 14 (53.8) | 3 (11.5) |
| Nausea | 4 (15.3) | 0 (0.0) |
| Rash | 4 (15.4) | 0 (0.0) |
| Anorexia | 9 (34.6) | 1 (3.8) |
| Vomiting | 9 (34.6) | 0 (0.0) |
| Stomatitis | 6 (23.1) | 0 (0.0) |
| Abdominal pain | 2 (7.6) | 0 (0.0) |
| Dyspnea | 1 (3.8) | 0 (0.0) |
| Constipation | 1 (3.8) | 0 (0.0) |