Table 2.
Association analysis results between the two image-based biomarkers (phenotypes) and the genomic biomarkers (genotypes) from Table 1 presented here within each ethic group. *SNP positions are based on the human reference sequence (NCBI Build 36.1).
| Quantile-normalized | Genomic biomarkers | All ethnic groups (179 subjects) |
Caucasian and African-American groups (170 subjects) |
Caucasian group (140 subjects) |
African-American group (30 subjects) |
||||
|---|---|---|---|---|---|---|---|---|---|
| Image-based biomarkers (Phenotypes) | (SNPs) (SNP position in Chr4*) | p-value | p-value after correction* | p-value | p-value after correction* | p-value | p-value after correction* | p-value | p-value after correction* |
| MaxEdgeGradient (Ref. 18) | 69630002 (rs451632) | 0.00026 | 0.022 | 0.00016 | 0.015 | 0.0023 | 0.14 | 0.038 | 0.98 |
| β (power law) (Ref. 31) | 70499290 (rs4148298) | 0.00044 | 0.035 | 0.0017 | 0.124 | 0.00037 | 0.030 | 0.81 | 1 |