Table 1.
Characteristics of the study population
| Colon | P Value | Rectal | P Value | |||
|---|---|---|---|---|---|---|
| Controls | Cases | Controls | Cases | |||
| n (%) | n (%) | n (%) | n (%) | |||
|
| ||||||
| Age | ||||||
| 30–39 | 40 (2.04) | 23 (1.48) | NA | 21 (2.19) | 19 (2.52) | NA |
| 40–49 | 128 (6.54) | 102 (6.56) | 101 (10.53) | 96 (12.73) | ||
| 50–59 | 326 (16.67) | 290 (18.65) | 243 (25.34) | 196 (25.99) | ||
| 60–69 | 673 (34.41) | 538 (34.60) | 329 (34.31) | 250 (33.16) | ||
| 70–79 | 789 (40.34) | 602 (38.71) | 265 (27.63) | 193 (25.60) | ||
| Center | ||||||
| Utah | 378 (19.33) | 249 (16.01) | NA | 365 (38.06) | 274 (36.34) | NA |
| KPMCP | 787 (40.24) | 744 (47.85) | 594 (61.94) | 480 (63.66) | ||
| Minnesota | 791 (40.44) | 562 (36.14) | ||||
| Race/Ethnicity | ||||||
| NHW | 1828 (93.46) | 1428 (91.83) | NA | 824 (85.92) | 625 (82.89) | NA |
| Hispanic | 75 (3.83) | 59 (3.79) | 63 (6.57) | 61 (8.09) | ||
| Black | 53 (2.71) | 68 (4.37) | 43 (4.48) | 29 (3.85) | ||
| Asian | NA | NA | 29 (3.02) | 39 (5.17) | ||
| Sex | ||||||
| Male | 1047 (53.53) | 870 (55.95) | NA | 541 (56.41) | 451 (59.81) | NA |
| Female | 909 (46.47) | 685 (44.05) | 418 (43.59) | 303 (40.19) | ||
| Dietary Variables | Median (IQR)1
|
Median (IQR)
|
||||
| Energy (Kcal) | 2134 (1615, 2829) | 2219 (1700, 2949) 85.29 (65.84, 113.20) | <.01 | 2380 (1752, 3133) | 2476 (1784, 3314) | 0.03 |
| Protein (gm) | 82.68 (62.59, 109.01) | 0.02 | 85.06 (64.05, 111.55) | 87.40 (63.90, 118.73) | 0.06 | |
| Saturated Fat (gm) | 26.83 (18.19, 39.09) | 28.94 (19.57, 43.13) | <.01 | 29.21 (19.66, 44.32) | 31.21 (21.12, 46.91) | 0.01 |
| Monounsaturated Fat (gm) | 26.24 (18.08, 38.00) | 28.64 (19.82, 41.84) | <.01 | 32.23 (21.50, 47.10) | 34.02 (23.03, 49.79) | 0.02 |
| Polyunsaturated (gm) Fat | 13.82 (9.90, 19.98) | 14.97 (10.49, 21.08) | <.01 | 20.40 (13.67, 29.27) | 21.54 (14.03, 30.46) | 0.06 |
| Trans-Fatty Acid (gm) | 4.94 (3.20, 7.51) | 5.66 (3.63, 8.48) | <.01 | 5.09 (3.23, 7.76) | 5.55 (3.51, 8.57) | 0.01 |
| Carbohyrates (gm) | 274 (210, 361) | 282 (219, 372) | 0.07 | 297 (218, 390) | 304 (221, 402) | 0.29 |
| Vitamin C (mg) | 148 (101, 210) | 147 (102, 209) | 0.86 | 152 (99, 215) | 145 (96, 215) | 0.36 |
| Folic Acid (mcg) | 354 (267, 469) | 354 (268, 465) | 0.96 | 357 (260, 476) | 352 (257, 468) | 0.90 |
| Calcium (mg) | 987 (685, 1393) | 975 (675, 1372) | 0.43 | 1020 (715, 1462) | 982 (690, 1405) | 0.67 |
| Vitamin D (mcg) | 5.85 (3.37, 9.05) | 5.70 (3.43, 8.91) | 0.93 | 6.57 (4.28, 9.86) | 6.89 (4.28, 10.06) | 0.28 |
| Lutein/Zeaxanthin(mcg) | 2266 (1537, 3383) | 2238 (1486, 3424) | 0.55 | 2673 (1738, 3995) | 2621 (1703, 3888) | 0.52 |
| Lycopene (mcg) | 5919 (3211, 9752) | 5912 (3235, 10027) | 0.32 | 7845 (4470, 13086) | 7838 (4136, 13607) | 0.97 |
| Alpha-tocopherol (mg) | 7.45 (5.24, 10.58) | 7.70 (5.35, 11.03) | 0.22 | 9.25 (6.39, 13.10) | 9.20 (6.47, 13.29) | 0.38 |
| Selenium (mcg) | 126 (96, 165) | 129 (99, 168) | 0.02 | 130 (95, 185) | 134 (101, 197) | 0.04 |
| Beta-carotene (mcg) | 3786 (2398, 6302) | 3990 (2431, 6354) | 0.65 | 3983 (2538, 6519) | 3845 (2353, 6296) | 0.48 |
| Mutagen Index | 624 (369, 943) | 659 (407, 1005) | 0.09 | 648 (366, 1040) | 731 (396, 1091) | 0.17 |
| Cruciferous Vegetables (serv./day) | 0.27 (0.09, 0.59) | 0.25 (0.09, 0.59) | 0.68 | 0.23 (0.07, 0.54) | 0.22 (0.07, 0.49) | 0.91 |
1
Medians and inter-quartile range (IQR) adjusted for age; p values are based on age adjusted log transformed means