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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Am J Clin Pathol. 2013 Feb;139(2):242–254. doi: 10.1309/AJCP2Z0TAGMUYJEB

Figure 3.

Figure 3

MYC protein expression in cases that differ in MYC and chromosome 8 copy number and correlated to MYC messenger RNA (mRNA) and patient overall survival. The percent MYC protein positive cells as determined by immunohistochemistry was compared among the 3 different MYC and chromosome 8 copy number groups using a 1-way analysis of variance (A). MYC protein positive and negative cases were evaluated for level of MYC mRNA (log2 transformed) (B). Lines represent the mean. A case was defined as positive for MYC protein if at least 40% of cells were stained within a 300-cell count. The Mann-Whitney 2-tailed t test was used to determine significance.