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. Author manuscript; available in PMC: 2015 Feb 15.
Published in final edited form as: Dev Biol. 2013 Nov 27;386(2):428–439. doi: 10.1016/j.ydbio.2013.11.015

Figure 6. DFO partially rescues hypomotility of trpm7 mutants.

Figure 6

DFO treatment increased spontaneous motility of 5-dpf, trpm7b508 mutant larvae. Automated analysis of motility was carried out as in Fig. 2. For each experiment, half of a single clutch of larvae from trpm7 heterozygous adults was treated with 50 μM DFO from 2–5 dpf. Motility of control larvae was unaffected by DFO treatment (Student’s t-test, p > 0.4). Motility of the trpm7 mutant was significantly increased by treatment with DFO in darkness (Student’s t-test, p < 0.05). Each group tested consisted of 23–24 animals. Error bars represent SEM. Asterisks, significantly different values.