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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2013 Jan 11;145(3):721–729. doi: 10.1016/j.jtcvs.2012.12.026

Table 4. Association of patient demographics, comorbid diseases and symptoms with urgent or emergent paraesophageal hernia repair.

Nonelective operation

Patient Demographics: (n, [%]) Overall
n=980
Elective
n=781
Nonelective
n=199
p-value Adjusted ORd 95% CI
Sex Female 733 (75) 595 (81) 138 (19) 0.055
Male 247 (25) 186 (75) 61 (25)

Age group at operation <50 60 (6) 51 (85) 9 (15) <0.001 ref ref
50-59 148 (15) 130 (88) 18 (12) 0.80 (0.33, 1.96)
60-69 261 (27) 234 (90) 27 (10) 0.61 (0.26, 1.42)
70-70 319 (33) 265 (83) 55 (17) 0.93 (0.42, 2.09)
80+ 192 (20) 102 (53) 90 (47) 2.66 (1.16, 6.10)

Body MassIndex by WHO classificationa Underweight 16 (2) 9 (56) 7 (44) <0.001 ref ref
Ideal 185 (19) 126 (68) 59 (32) 0.50 (0.13, 1.73)
Overweight 356 (37) 295 (83) 61 (17) 0.35 (0.10, 1.12)
Obese 258 (27) 220 (85) 38 (15) 0.36 (0.10, 1.27)
Severely obese 149 (15) 127 (85) 22 (15) 0.42 (0.12, 1.54)

Preoperative Hernia Size (%)b 30-49% 174 (18) 157 (90) 17 (10) <0.001 ref ref
50-74% 354 (36) 300 (85) 54 (15) 1.40 (0.74, 2.60)
75-99% 212 (22) 159 (75) 53 (25) 2.60 (1.25, 4.88)
Intrathoracic Stomach 240 (24) 165 (69) 75 (31) 3.00 (1.59, 5.58)

History of Pretreatment Charlson-defined patient comorbidity

Myocardial infarction or revascularization No 833 (85) 677 (81) 156 (19) 0.005 1.27 (0.80, 2.02)
Yes 147 (15) 104 (71) 43 (29)

Congestive heart failure No 941 (96) 761 (81) 180 (19) <0.001 1.84 (0.83, 4.05)
Yes 39 (4) 20 (51) 19 (48)

Cerebral vascular accident or transient attack No 904 (92) 737 (82) 167 (18) <0.001 1.60 (0.87, 2.83)
Yes 76 (8) 44 (58) 32 (42)

Dementia No 937 (96) 763 (81) 174 (19) <0.001 2.43 (1.13, 5.22)
Yes 43 (4) 18 (42) 25 (58)

Pulmonary disease No 690 (70) 550 (80) 140 (20) 1.000
Yes 290 (30) 231 (80) 59 (20)

Connective Tissue Disorder No 942 (96) 750 (80) 192 (20) 1.000
Yes 38 (4) 31 (82) 7 (18)

Peptic Ulcer Disease No 794 (81) 655 (82) 139 (18) <0.001 2.20 (1.50, 3.30)
Yes 186 (19) 126 (68) 60 (32)

Diabetes requiring medical therapy No 909 (93) 728 (80) 181 (20) 0.284
Yes 71 (7) 53 (75) 18 (25)

Malignancy in the past 5 years No 924 (94) 740 (80) 184 (20) 0.231
Yes 56 (6) 41 (73) 15 (27)

Rare CCI variablesc No 939 (96) 753 (80) 186 (20) 0.074
Yes 41 (4) 28 (68) 13 (32)

Preoperative Symptoms

Respiratory Symptoms No 232 (34) 164 (71) 68 (29) <0.001
Yes 450 (66) 373 (83) 77 (17)

Chest and/or Abdominal pain No 273 (32) 236 (86) 37 (14) 0.001
Yes 589 (68) 449 (76) 140 (24)

Heartburn No 335 (35) 226 (67) 109 (33) <0.001
Yes 626 (65) 545 (87) 81 (13)

Dysphagia No 533 (55) 418 (78) 115 (22) 0.122
Yes 431 (45) 356 (83) 75 (17)

Regurgitation No 377 (39) 316 (84) 61 (16) 0.014
Yes 590 (61) 456 (77) 134 (23)

Bloating No 619 (66) 483 (78) 136 (22) 0.016
Yes 325 (34) 275 (85) 50 (15)
a

Underweight BMI <18.5; Ideal BMI 18.5 up to 25; Overweight BMI 25 up to 30; Obese BMI 30 up to 35; Severely Obese BMI 35 or greater

b

Percent of stomach within the mediastinum by barium esophagram, preoperative endoscopy or by intraoperative description

c

Rare CCI variables (<3% of cohort) include peripheral vascular disease, renal disease, liver disease, diabetes mellitus with organ damage, hemiplegia or paraplegia, lymphoma, leukemia, metastatic cancer and acquired immunodeficiency syndrome

d

Each adjusted for the other variables in the model (age group, BMI, size of hernia, myocardial infarction, congestive heart failure, cerebral vascular accident or transient attack, dementia, peptic ulcer disease)

BMI - body mass index (kg/m2); WHO - World Health Organization; CCI - Charlson Comorbidity Index