Table 1.
Overall (n=1,417)
|
PA (n=448a)
|
Non-PA (n=969a)
|
|||||||
---|---|---|---|---|---|---|---|---|---|
PA (n=448a) | Non-PA (n=969a) | P-value for region comparison | PMI arm (n=247a) | UC arm (n=201a) | P-value | PMI arm (n=513a) | UC arm (n=456a) | P-value | |
Male, n (%) | 284 (63.4) | 454 (46.9) | <0.001 | 162 (65.6) | 122 (60.7) | 0.285 | 244 (47.6) | 210 (46.1) | 0.638 |
Age, years, mean ± SD | 62.5±9.5 | 59.1±10.1 | <0.001 | 61.5±9.8 | 63.6±8.9 | 0.019 | 59.2±10.0 | 58.9±10.3 | 0.606 |
Current smoker, n (%) | 121 (27.3) | 424 (43.8) | <0.001 | 74 (30.2) | 47 (23.6) | 0.121 | 233 (45.4) | 191 (41.9) | 0.268 |
BMI, kg/m2, mean ± SD | 25.9±3.8 | 30.1±5.0 | <0.001 | 25.6±3.8 | 26.3±3.7 | 0.064 | 30.2±5.1 | 30.0±5.0 | 0.694 |
SBP, mmHg, mean ± SDb | 147.6±17.2 | 147.5±13.9 | 0.976 | 151.0±17.4 | 143.3±15.9 | <0.001 | 150.0±13.5 | 144.8±13.8 | <0.001 |
DBP, mmHg, mean ± SDb | 86.1±10.5 | 89.1±8.5 | <0.001 | 87.9±11.1 | 84.1±9.2 | <0.001 | 90.6±8.0 | 87.5±8.9 | <0.001 |
Heart rate, bpm, mean ± SD | 72.8±10.6 | 73.7±9.4 | 0.118 | 72.6±10.5 | 73.2±10.7 | 0.544 | 74.7±9.3 | 72.7±9.5 | 0.001 |
TC, mg/dL, mean ± SD | 194.3±30.1 | 200.4±29.7 | <0.001 | 194.6±30.3 | 194.0±29.8 | 0.831 | 201.7±29.6 | 198.8±29.9 | 0.123 |
LDL-C, mg/dL, mean ± SD | 113.7±28.5 | 121.1±26.8 | <0.001 | 114.2±28.3 | 113.0±28.7 | 0.659 | 121.9±26.3 | 120.2±27.5 | 0.335 |
HDL-C, mg/dL, mean ± SD | 47.2±12.9 | 47.9±14.0 | 0.384 | 47.2±12.3 | 47.2±13.6 | 0.997 | 47.8±14.1 | 48.1±13.7 | 0.749 |
TG, mg/dL, mean ± SD | 170.9±84.0 | 161.5±82.9 | 0.049 | 169.6±84.9 | 172.6±83.1 | 0.711 | 165.6±86.1 | 156.7±78.9 | 0.096 |
Type 2 diabetes, n (%) | 263 (58.7) | 337 (34.8) | <0.001 | 143 (57.9) | 120 (59.7) | 0.699 | 181 (35.3) | 156 (34.2) | 0.727 |
Framingham 10-year CHD risk (%),11 mean ± SD | 21.7±12.3 | 17.9±10.4 | <0.001 | 22.0±12.0 | 21.3±12.8 | 0.606 | 19.0±10.6 | 16.7±10.0 | <0.001 |
Notes:
Treated patients with baseline and one or more postbaseline efficacy measurements
BP values were measured at baseline (week 0), whereas information on all of the other variables listed were collected during screening.
Abbreviations: bpm, beats per minute; BMI, body mass index; BP, blood pressure; CHD, coronary heart disease; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; PA, Pacific Asian; PMI, proactive multifactorial intervention; SBP, systolic blood pressure; SD, standard deviation; TC, total cholesterol; TG, triglyceride; UC, usual care.