Table 1.
Baseline characteristics and demographics in PA and non-PA regions
| Overall (n=1,417)
|
PA (n=448a)
|
Non-PA (n=969a)
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| PA (n=448a) | Non-PA (n=969a) | P-value for region comparison | PMI arm (n=247a) | UC arm (n=201a) | P-value | PMI arm (n=513a) | UC arm (n=456a) | P-value | |
| Male, n (%) | 284 (63.4) | 454 (46.9) | <0.001 | 162 (65.6) | 122 (60.7) | 0.285 | 244 (47.6) | 210 (46.1) | 0.638 |
| Age, years, mean ± SD | 62.5±9.5 | 59.1±10.1 | <0.001 | 61.5±9.8 | 63.6±8.9 | 0.019 | 59.2±10.0 | 58.9±10.3 | 0.606 |
| Current smoker, n (%) | 121 (27.3) | 424 (43.8) | <0.001 | 74 (30.2) | 47 (23.6) | 0.121 | 233 (45.4) | 191 (41.9) | 0.268 |
| BMI, kg/m2, mean ± SD | 25.9±3.8 | 30.1±5.0 | <0.001 | 25.6±3.8 | 26.3±3.7 | 0.064 | 30.2±5.1 | 30.0±5.0 | 0.694 |
| SBP, mmHg, mean ± SDb | 147.6±17.2 | 147.5±13.9 | 0.976 | 151.0±17.4 | 143.3±15.9 | <0.001 | 150.0±13.5 | 144.8±13.8 | <0.001 |
| DBP, mmHg, mean ± SDb | 86.1±10.5 | 89.1±8.5 | <0.001 | 87.9±11.1 | 84.1±9.2 | <0.001 | 90.6±8.0 | 87.5±8.9 | <0.001 |
| Heart rate, bpm, mean ± SD | 72.8±10.6 | 73.7±9.4 | 0.118 | 72.6±10.5 | 73.2±10.7 | 0.544 | 74.7±9.3 | 72.7±9.5 | 0.001 |
| TC, mg/dL, mean ± SD | 194.3±30.1 | 200.4±29.7 | <0.001 | 194.6±30.3 | 194.0±29.8 | 0.831 | 201.7±29.6 | 198.8±29.9 | 0.123 |
| LDL-C, mg/dL, mean ± SD | 113.7±28.5 | 121.1±26.8 | <0.001 | 114.2±28.3 | 113.0±28.7 | 0.659 | 121.9±26.3 | 120.2±27.5 | 0.335 |
| HDL-C, mg/dL, mean ± SD | 47.2±12.9 | 47.9±14.0 | 0.384 | 47.2±12.3 | 47.2±13.6 | 0.997 | 47.8±14.1 | 48.1±13.7 | 0.749 |
| TG, mg/dL, mean ± SD | 170.9±84.0 | 161.5±82.9 | 0.049 | 169.6±84.9 | 172.6±83.1 | 0.711 | 165.6±86.1 | 156.7±78.9 | 0.096 |
| Type 2 diabetes, n (%) | 263 (58.7) | 337 (34.8) | <0.001 | 143 (57.9) | 120 (59.7) | 0.699 | 181 (35.3) | 156 (34.2) | 0.727 |
| Framingham 10-year CHD risk (%),11 mean ± SD | 21.7±12.3 | 17.9±10.4 | <0.001 | 22.0±12.0 | 21.3±12.8 | 0.606 | 19.0±10.6 | 16.7±10.0 | <0.001 |
Notes:
a
Treated patients with baseline and one or more postbaseline efficacy measurements
b
BP values were measured at baseline (week 0), whereas information on all of the other variables listed were collected during screening.
Abbreviations: bpm, beats per minute; BMI, body mass index; BP, blood pressure; CHD, coronary heart disease; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; PA, Pacific Asian; PMI, proactive multifactorial intervention; SBP, systolic blood pressure; SD, standard deviation; TC, total cholesterol; TG, triglyceride; UC, usual care.