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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Mar 17;1803(7):832–839. doi: 10.1016/j.bbamcr.2010.03.003

Figure 2.

Figure 2

Histological pictures of E17 control HER4heart+/− (A, C) and HER4heart−/− (B, D) lungs. Representative light microscopic images from cryosections stained with hematoxilin and eosin. HER4heart−/− (B) lungs have fewer transitory ducts and saccules compared to HER4heart+/− control lungs (A). A higher resolution shows more epithelial cells surrounding the air spaces in control lungs (C). HER4heart−/− (D) lungs have less sacculi and show accumulation of tissue containing mesenchyme cells. Morphometric evaluations revealed an increased volume density of the septal tissue and a decreased volume density of the airspace in HER4heart−/− lungs.