Table 1.
—Population Information on Groups Included in Study
| Included in Study | |||
| Variable | Control (12,238) | SSRI/SNRI Admission (2,471) | Rank Sum P Value |
| Demographics | |||
| Sex, % male | 61 | 44 | < .05 |
| Age, y | 66, IQR 26 | 64, IQR 25 | .4 |
| SAPS | 13, IQR 7 | 13, IQR 8 | < .05 |
| ICU type, % | |||
| CCU | 23 | 21 | .05 |
| CSRU | 38 | 33 | < .05 |
| MICU | 33 | 40 | < .05 |
| SICU | 6 | 5 | .2 |
| Selected acute diagnoses, % | |||
| Acute coronary syndrome (serum troponin > 0.5 ng/mL) | 8 | 7 | .2 |
| Sepsis (Martin criteriaa) | 3 | 4 | .7 |
| Comorbidities by ICD-9, % | |||
| COPD | 7 | 11 | < .05 |
| Diabetes | 17 | 21 | < .05 |
| Cardiovascular disease | 70 | 68 | .06 |
| Treatments, % | |||
| Ventilator use | 55 | 49 | < .05 |
| Vasopressor use | 39 | 31 | < .05 |
| Blood products transfused, mL | |||
| Total RBC volume | 750, IQR 1,125 | 750, IQR 1,125 | .2 |
| Total FFP volume | 608, IQR 866 | 614, IQR 895 | .6 |
| Total platelet volume | 325, IQR 487 | 27,5 IQR 380 | .07 |
Binary variables reported as prevalence percentages, continuous variables reported as data median with IQR, lengths of stay reported as data mean SD. CCU = coronary care unit; CSRU = cardiac surgery recovery unit; FFP = fresh frozen plasma; ICD-9 = International Classification of Diseases, Ninth Revision; IQR = interquartile range; MICU = medical ICU; SAPS = Simplified Acute Physiology Score; SICU = surgical ICU; SNRI = serotonin norepinephrine reuptake inhibitor; SSRI = selective serotonin reuptake inhibitor.
a
As described in Martin et al.20