Table 4.
Drug | Population on Medication | Hospital Mortality Rate in Positives, % | Dissociation Constant for Serotonin Transportera |
Citalopram | 622 | 9 | 1.16 |
Escitalopram | 203 | 5 | Unknownb |
Fluoxetine | 388 | 10 | 0.81 |
Sertraline | 555 | 14 | 0.29 |
Paroxetine | 406 | 12 | 0.13 |
The hospital mortality rate in the control group is 10%.
Lower dissociation constant denotes a higher degree of serotonin reuptake inhibition. From Tatsumi et al.14
Escitalopram is the active s-enantiomer of citalopram and is, thus, presumed to have a similar dissociation constant.