Skip to main content
. 2013 Dec 26;145(4):745–752. doi: 10.1378/chest.13-1722

Table 4.

—Proportion of In-Hospital Death for Specific Drugs as Compared With Those in the Control Population

Drug Population on Medication Hospital Mortality Rate in Positives, % Dissociation Constant for Serotonin Transportera
Citalopram 622 9 1.16
Escitalopram 203 5 Unknownb
Fluoxetine 388 10 0.81
Sertraline 555 14 0.29
Paroxetine 406 12 0.13

The hospital mortality rate in the control group is 10%.

a

Lower dissociation constant denotes a higher degree of serotonin reuptake inhibition. From Tatsumi et al.14

b

Escitalopram is the active s-enantiomer of citalopram and is, thus, presumed to have a similar dissociation constant.