Table 1.
Baseline Characteristics of 308 Patients With Chronic HCV Genotype 1 Infection
| Characteristic | Distribution |
|---|---|
| Demographics | |
| Mean age, y (SD) | 56.1 (5.5) |
| Race, % | |
| Caucasian | 75.0 |
| African American | 25.0 |
| Clinical characteristics, % | |
| FibroSURE-ActiTest | |
| F0–F3 | 61.6 |
| F3/F4–F4 | 38.4 |
| Necroinflammatory | |
| A0–A2 | 67.4 |
| A2/3–A3 | 32.6 |
| HCV genotype | |
| 1 (unspecified) | 3.6 |
| 1a | 70.1 |
| 1b | 26.3 |
| Overall treatment ineligible, % | 36.0 |
| Reasons for treatment ineligibility, % | |
| Physical comorbidity | 19.5 |
| Coronary artery disease | 2.6 |
| Other cardiac conditions | 0.3 |
| COPD | 3.2 |
| ESRD | 0.0 |
| Cancer | 4.5 |
| Decompensated cirrhosis | 4.5 |
| Othera | 9.7 |
| Mental comorbidity | 19.2 |
| Current drug/alcohol use | 13.0 |
| Depression | 10.1 |
| Other psychiatric diagnosesb | 0.6 |
| Other barriers | 8.4 |
| Noncompliance with evaluation | 1.9 |
| Homelessness | 0.3 |
| Noninterest in treatment | 3.6 |
| Failed previous treatment | 2.6 |
| Eventually treated, % | 11.0 |
COPD, chronic obstructive pulmonary disease; ESRD, end-stage renal disease.
a
Included were anemia, awaiting hip surgery, cerebrovascular disease, colitis, diabetes, glaucoma, hyperthyroidism, hypothyroidism, neutropenia, obesity, pancytopenia, peripheral vascular disease, retinal vein occlusion, seizures, suspicious mass, suspicious lesions, thrombosis, and thrombocytopenia.
b
Included memory issues.