. Author manuscript; available in PMC: 2014 Apr 1.

Published in final edited form as: J Nat Prod. 2005 Nov;68(11):1592–1597. doi: 10.1021/np050293f

Table 2. Cytotoxicity and Antimicrofilament Data of 1, 2, and 3.

	cytotoxicity^a^,^b			antimicrofilament activity^c

	L1210	C38	CFU-GM	1 μg/mL	2.5 μg/mL	5 μg/mL	10 μg/mL	15 μg/mL	25 μg/mL
1		150					+Δ	++ΔΔ	++++ΔΔ
2	250	350	250	ND	ND	ND	ND	ND	ND
3	500	400	500	+	++	++++

Cytotoxicity quoted in zone units.³³ L1210 = murine leukemia, C38 = murine colon, CFU-GM = normal bone marrow.

Concentration of analyte 15 μg/disk.

Assays performed in A-10 cells (rat smooth muscle cells).^{34 +} Loss of microfilament. ⁺⁺Additional loss of microfilament. ⁺⁺⁺⁺Total loss of microfilament network. Δ Cell Loss. ND Not determined.