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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Mov Disord. 2009 Jul 15;24(9):1267–1279. doi: 10.1002/mds.22504

TABLE 1.

Autoantibody findings in PANDAS

Reference Method Clinical syndrome (number of patients) Finding
70 IF PANDAS (N = 22) vs. uncomplicated Strep. infection (n = 22) Positive binding in 64% vs. 9%
71 ELISA PANDAS (n = 15) vs. control (n = 15) No difference in patients compared to controls
72 ELISA PANDAS (n = 40) vs. controls (n = 190) Elevated mean ELISA in PANDAS vs. controls
69 ELISA PANDAS (n = 48) vs. TS (N = 46) vs. control (n = 43) No difference in patients compared to controls
72 WB PANDAS (n = 40) vs. controls (n = 190) Positive binding in 92% vs. 5%
71 WB PANDAS (n = 15) vs. controls (n = 15) No difference in binding between groups
69 WB PANDAS (n = 48) vs. controls (n = 43) No difference in binding between groups
73 Cell surf. PANDAS (n = 16) vs. TS, OCD, ADHD (n = 25) Positive binding to cell surface in PANDAS more than TS, OCD, ADHD

IF, immunofluorescence; ELISA, enzyme linked immunosorbent assay; WB, Western blotting; Cell surf, cell surface binding to live neurons; PANDAS, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection; TS, Tourette syndrome; OCD, obsessive-compulsive disorder; ADHD, attention deficit hyperactivity disorder.